Math 297/Biol 497

Biomolecular Computing in Nature

Assignment 10

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Use the three intramolecular operations ld, hi and dlad, one at a time, to derive the pre-chromosome breakage macronuclear version of the DNA polymerase alpha gene of

1. Stylonychia Lemnae (Accession number AF194337, AF194336)

2. Oxytricha trifallax (Accession number DQ525914)

from its micronuclear precursor. Carefully display for each step the resulting molecules, and the important features used to carry out that step.

Literature:

Stylonychia Lemnae